20+ Years of Research
Backed by Science
The Prysm iO isn't a wellness gimmick. It's a clinically-validated measurement tool with decades of peer-reviewed research supporting every reading.
Spectral Rai™ Technology
At the heart of the Prysm iO is our patent-pending Spectral Rai™ technology. Each scan fires more than 700,000 hyperspectral absorption measurements at the skin in just 15 seconds, using resonance Raman spectroscopy to detect carotenoid molecules with extraordinary precision.
A machine learning calibration engine then maps these measurements against validated reference populations to deliver your personalised Prysm Score — a number that reflects your antioxidant defence in real time.
The Research Behind Your Score
Peer-reviewed science underpins every aspect of how your Prysm Score is calculated.
Carotenoid Biomarkers
Carotenoids are fat-soluble antioxidants found in fruits and vegetables. Research spanning two decades has established skin carotenoid levels as a reliable, non-invasive biomarker for overall nutritional status and antioxidant defence.
Mayne et al. (2010). American Journal of Clinical Nutrition.
Raman Spectroscopy
Resonance Raman spectroscopy is used to measure carotenoid concentrations in the skin. This technology is clinically validated against blood serum carotenoid measurements, with strong correlation across diverse populations.
Ermakov et al. (2005). Journal of Biomedical Optics.
Oxidative Stress & Disease
Oxidative stress — caused by an imbalance between free radicals and antioxidants — is implicated in cardiovascular disease, cancer, diabetes, and accelerated ageing. Higher carotenoid levels indicate greater antioxidant capacity.
Lobo et al. (2010). Pharmacognosy Review.
Supplement Efficacy
Clinical trials have shown that carotenoid-rich supplements — when properly formulated and absorbed — significantly raise Prysm Scores within weeks. The score provides objective evidence of supplement effectiveness.
Pharmanex® LifePak® Clinical Studies (2003–2023).
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